SCOPe 2.08: Domain d6gcxa_: 6gcx A:

Lineage for d6gcxa_ (6gcx A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Focal adhesion kinase 1 (fak) [103292] (2 species)
   PTK group; FAK subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [187336] (5 PDB entries)

8. Domain d6gcxa_: 6gcx A: [368399]
   automated match to d2j0la_
   complexed with euw, so4

Details for d6gcxa_

PDB Entry: 6gcx, 1.55 Å

PDB Description: focal adhesion kinase catalytic domain in complex with irreversible inhibitor

PDB Compounds: (A:) Focal adhesion kinase 1

SCOPe Domain Sequences for d6gcxa_:

Sequence, based on SEQRES records:

>d6gcxa_ d.144.1.7 (A:) Focal adhesion kinase 1 (fak) {Chicken (Gallus gallus) [TaxId: 9031]}
rdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflqea
ltmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlst
alayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwmape
sinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptly
slmtkcwaydpsrrprftelkaqlstileeeklq

Sequence, based on observed residues (ATOM records):

>d6gcxa_ d.144.1.7 (A:) Focal adhesion kinase 1 (fak) {Chicken (Gallus gallus) [TaxId: 9031]}
rdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlstal
ayleskrfvhrdiaarnvlvsatdcvklgdfglsrlpikwmapesinfrrftsasdvwmf
gvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrpr
ftelkaqlstileeeklq

Timeline for d6gcxa_:

• d6gcxa_ first appeared in SCOPe 2.07