Lineage for d6ebwa_ (6ebw A:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. Protein automated matches [190417] (36 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1454 PDB entries)
  8. Domain d6ebwa_: 6ebw A: [368398]
    automated match to d4foda_
    complexed with j3y

Details for d6ebwa_

PDB Entry: 6ebw (more details), 2.46 Å

PDB Description: halk in complex with compound 9 (6-(((1s)-1-(5-fluoropyridin-2-yl) ethyl)amino)-1-(3-methyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-3- yl)(morpholin-4-yl)methanone
PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d6ebwa_:

Sequence, based on SEQRES records: (download)

>d6ebwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktlpev
cseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprp
sqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmar
diyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksn
qevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvint
alpi

Sequence, based on observed residues (ATOM records): (download)

>d6ebwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ycftssisdlkevprknitlirglghfgevyegqvssplqvavktlpevcseqdeldflm
ealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprppsslamldllh
vardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardlpvkwmppeafm
egiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrim
tqcwqhqpedrpnfaiilerieyctqdpdvintalpi

SCOPe Domain Coordinates for d6ebwa_ are not available.

Timeline for d6ebwa_: