Lineage for d6a7ea_ (6a7e A:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [53607] (79 PDB entries)
  8. Domain d6a7ea_: 6a7e A: [367307]
    automated match to d1kmva_
    complexed with 9qr, ndp

Details for d6a7ea_

PDB Entry: 6a7e (more details), 1.85 Å

PDB Description: human dihydrofolate reductase complexed with nadph and bt2
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d6a7ea_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6a7ea_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

SCOPe Domain Coordinates for d6a7ea_ are not available.

Timeline for d6a7ea_: