Lineage for d6a7ca_ (6a7c A:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [53607] (79 PDB entries)
  8. Domain d6a7ca_: 6a7c A: [367306]
    automated match to d1kmva_
    complexed with 9qo, ndp, so4

Details for d6a7ca_

PDB Entry: 6a7c (more details), 2.06 Å

PDB Description: human dihydrofolate reductase complexed with nadph and bt1
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d6a7ca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6a7ca_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

SCOPe Domain Coordinates for d6a7ca_ are not available.

Timeline for d6a7ca_: