Lineage for d6hmeb_ (6hme B:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
    CMGC group; CK2 subfamily; serine/threonine kinase
  7. Species Human (Homo sapiens) [TaxId:9606] [75559] (180 PDB entries)
  8. Domain d6hmeb_: 6hme B: [366876]
    automated match to d3wara_
    complexed with cl, edo, fxb, na, so4

Details for d6hmeb_

PDB Entry: 6hme (more details), 1.85 Å

PDB Description: low-salt structure of protein kinase ck2 catalytic subunit (isoform ck2alpha; csnk2a1 gene product) in complex with the indenoindole-type inhibitor thn27
PDB Compounds: (B:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d6hmeb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6hmeb_ d.144.1.7 (B:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqar

SCOPe Domain Coordinates for d6hmeb_ are not available.

Timeline for d6hmeb_:

Domains from other chains:
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d6hmea_