SCOPe 2.08: Domain d6gvcr_: 6gvc R:

Lineage for d6gvcr_ (6gvc R:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.116: GTPase activation domain, GAP [48349] (1 superfamily)
   multihelical

4. Superfamily a.116.1: GTPase activation domain, GAP [48350] (3 families)

5. Family a.116.1.0: automated matches [227202] (1 protein)
   not a true family

6. Protein automated matches [226932] (4 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [366768] (1 PDB entry)

8. Domain d6gvcr_: 6gvc R: [366769]
   Other proteins in same PDB: d6gvca1, d6gvca2, d6gvcb1, d6gvcb2, d6gvcc1, d6gvcc2, d6gvcd1, d6gvcd2
   automated match to d3byic_
   complexed with atp, edo, lab, mg

Details for d6gvcr_

PDB Entry: 6gvc, 2.6 Å

PDB Description: structure of arhgap12 bound to g-actin

PDB Compounds: (R:) Rho GTPase-activating protein 12

SCOPe Domain Sequences for d6gvcr_:

Sequence, based on SEQRES records:

>d6gvcr_ a.116.1.0 (R:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
qkktkknlkkfltrrptlqavrekgyikdqvfgsnlanlcqrengtvpkfvklciehvee
hgldvdgiyrvsgnlaviqklrfavnhdekldlndskwedihvitgalkmffrelpeplf
tfnhfndfvnaikqeprqrvtavkdlirqlpkpnqdtmqilfrhlkrviengeknrmtyq
siaivfgptllkperetgniavhtvyqnqivelillelstvfg

Sequence, based on observed residues (ATOM records):

>d6gvcr_ a.116.1.0 (R:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
qkktkknlkkfltrrptlqavrekgyikdqvfgsnlanlcqrengtvpkfvklciehvee
hgldvdgiyrvsgnlaviqklrfavnhdekldlndskwedihvitgalkmffrelpeplf
tfnhfndfvnaikqeprqrvtavkdlirqlpkpnqdtmqilfrhlkrviengeknrmtyq
siaivfgptllkperhtvyqnqivelillelstvfg

Timeline for d6gvcr_:

• d6gvcr_ first appeared in SCOPe 2.07