SCOPe 2.08: Domain d6g3cb_: 6g3c B:

Lineage for d6g3cb_ (6g3c B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6g3cb_: 6g3c B: [366767]
   automated match to d5ut2a_
   complexed with edo, ekt

Details for d6g3cb_

PDB Entry: 6g3c, 1.6 Å

PDB Description: crystal structure of jak2-v617f pseudokinase domain in complex with compound 2

PDB Compounds: (B:) Tyrosine-protein kinase

SCOPe Domain Sequences for d6g3cb_:

Sequence, based on SEQRES records:

>d6g3cb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhkirnedlifneslgqgtftkifkgvrrevgdygqlhetevllkvldkahrnysesffe
aasmmsklshkhlvlnygvcfcgdenilvqefvkfgsldtylkknkncinilwklevakq
laaamhfleentlihgnvcaknillireedrktgnppfiklsdpgisitvlpkdilqeri
pwvppecienpknlnlatdkwsfgttlweicsggdkplsaldsqrklqfyedrhqlpapk
aaelanlinncmdyepdhrpsfraiirdlnsl

Sequence, based on observed residues (ATOM records):

>d6g3cb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhkirnedlifneslgqgtftkifkgvrrevgdygqlhetevllkvldkahrnysesffe
aasmmsklshkhlvlnygvcenilvqefvkfgsldtylkknkncinilwklevakqlaaa
mhfleentlihgnvcaknillireedrktgnppfiklsdpgisitvlpkdilqeripwvp
pecienpknlnlatdkwsfgttlweicsggdkplsaldsqrklqfyedrhqlpapkaael
anlinncmdyepdhrpsfraiirdlnsl

Timeline for d6g3cb_:

• d6g3cb_ first appeared in SCOPe 2.07