Lineage for d6hrta_ (6hrt A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2983276Protein automated matches [190091] (20 species)
    not a true protein
  7. 2983389Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)
  8. 2983540Domain d6hrta_: 6hrt A: [366553]
    automated match to d5j87b_
    complexed with gmw

Details for d6hrta_

PDB Entry: 6hrt (more details), 1.36 Å

PDB Description: crystal structure of btk kinase domain complexed with 12-(6-tert- butyl-8-fluoro-1-oxo-phthalazin-2-yl)-9-hydroxy-6-methyl-4-[[5- (morpholine-4-carbonyl)-2-pyridyl]amino]-6-azatricyclo[, 7]pentadeca-1(15),2(7),3,11,13-pentaen-5-one
PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d6hrta_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6hrta_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d6hrta_:

Click to download the PDB-style file with coordinates for d6hrta_.
(The format of our PDB-style files is described here.)

Timeline for d6hrta_: