SCOPe 2.08: Domain d6nh8d_: 6nh8 D:

Lineage for d6nh8d_ (6nh8 D:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (89 PDB entries)

8. Domain d6nh8d_: 6nh8 D: [366265]
   automated match to d3e7sa_
   complexed with btb, cl, gd, gol, h4b, hem, kms, zn

Details for d6nh8d_

PDB Entry: 6nh8, 1.8 Å

PDB Description: structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4- trifluorophenethyl)-4-methylpyridin-2-amine

PDB Compounds: (D:) Endothelial nitric oxide synthase splice variant eNOS13A

SCOPe Domain Sequences for d6nh8d_:

Sequence, based on SEQRES records:

>d6nh8d_ d.174.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kfprvknwevgsitydtlsaqaqqdgpctprrclgslvfprklqgrpspgppapeqllsq
ardfinqyyssikrsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvg
riqwgklqvfdardcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwns
qlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllp
pelvlevplehptlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrn
lcdphryniledvavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatas
fmkhleneqkarggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d6nh8d_ d.174.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kfprvknwevgsitydtlsaqaqqdgpctprrclgslvfpapeqllsqardfinqyyssi
krsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgriqwgklqvfda
rdcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsqlvryagyrqqd
gsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllppelvlevplehp
tlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnlcdphryniled
vavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasfmkhleneqkar
ggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Timeline for d6nh8d_:

• d6nh8d_ first appeared in SCOPe 2.07