SCOPe 2.08: Domain d6adxa1: 6adx A:183-481

Lineage for d6adxa1 (6adx A:183-481)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (7 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein automated matches [226986] (8 species)
   not a true protein

7. Species Zika virus (strain mr 766) [TaxId:64320] [327262] (9 PDB entries)

8. Domain d6adxa1: 6adx A:183-481 [365717]
   Other proteins in same PDB: d6adxa2
   automated match to d5jpsa1
   complexed with adp, mn

Details for d6adxa1

PDB Entry: 6adx, 1.75 Å

PDB Description: crystal structure of the zika virus ns3 helicase (adp-mn2+ complex, form 1)

PDB Compounds: (A:) Serine protease NS3

SCOPe Domain Sequences for d6adxa1:

Sequence, based on SEQRES records:

>d6adxa1 c.37.1.14 (A:183-481) automated matches {Zika virus (strain mr 766) [TaxId: 64320]}
mlkkkqltvldlhpgagktrrvlpeivreaikkrlrtvilaptrvvaaemeealrglpvr
ymttavnvthsgteivdlmchatftsrllqpirvpnynlnimdeahftdpssiaargyis
trvemgeaaaifmtatppgtrdafpdsnspimdtevevperawssgfdwvtdhsgktvwf
vpsvrngneiaacltkagkrviqlsrktfetefqktknqewdfvittdisemganfkadr
vidsrrclkpvildgervilagpmpvthasaaqrrgrigrnpnkpgdeymygggcaetd

Sequence, based on observed residues (ATOM records):

>d6adxa1 c.37.1.14 (A:183-481) automated matches {Zika virus (strain mr 766) [TaxId: 64320]}
mlkkkqltvldlhpgagktrrvlpeivreaikkrlrtvilaptrvvaaemeealrglpvr
ymttavnveivdlmchatftsrllqpirvpnynlnimdeahftdpssiaargyistrvem
geaaaifmtatppgtrdafpdsnspimdtevevperawssgfdwvtdhsgktvwfvpsvr
ngneiaacltkagkrviqlsrktfetefqktknqewdfvittdisemganfkadrvidsr
rclkpvildgervilagpmpvthasaaqrrgrigrnpnkpgdeymygggcaetd

Timeline for d6adxa1:

• d6adxa1 first appeared in SCOPe 2.07