SCOPe 2.07: Domain d6dfnb_: 6dfn B:

Lineage for d6dfnb_ (6dfn B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d6dfnb_: 6dfn B: [365071]
   automated match to d3q95b_
   complexed with g91, g9j, gol, ni

Details for d6dfnb_

PDB Entry: 6dfn, 2.1 Å

PDB Description: crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d6dfnb_:

Sequence, based on SEQRES records:

>d6dfnb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltshdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemld
a

Sequence, based on observed residues (ATOM records):

>d6dfnb_ a.123.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdlt
shdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllat
ssrfrmmnlqgeefvclksiillnsgleekdhihrvldkitdtlihlmakagltlqqqhq
rlaqlllilshirhmsnkgmehlysmksydlllemlda

Timeline for d6dfnb_:

• d6dfnb_ is new in SCOPe 2.07-stable
  
• d6dfnb_ appears in the current release, SCOPe 2.08