SCOPe 2.08: Domain d6egab_: 6ega B:

Lineage for d6egab_ (6ega B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6egab_: 6ega B: [365046]
   automated match to d2oicd_
   complexed with co, j8a, so4

Details for d6egab_

PDB Entry: 6ega, 2.51 Å

PDB Description: irak4 in complex with a type ii inhibitor

PDB Compounds: (B:) interleukin-1 receptor-associated kinase 4

SCOPe Domain Sequences for d6egab_:

Sequence, based on SEQRES records:

>d6egab_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditt
eelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppl
swhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtv
mtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeei
edeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta

Sequence, based on observed residues (ATOM records):

>d6egab_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaalkqqfd
qeikvmakcqhenlvellgfssdgdlclvyvympngslldrlscldgtpplswhmrckia
qgaanginflhenhhihrdiksanilldeaftakisdfvgttaymapealrgeitpksdi
ysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamy
svasqclhekknkrpdikkvqqllqemta

Timeline for d6egab_:

• d6egab_ first appeared in SCOPe 2.07