SCOPe 2.08: Domain d6ffga1: 6ffg A:344-455

Lineage for d6ffga1 (6ffg A:344-455)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d6ffga1: 6ffg A:344-455 [363191]
   Other proteins in same PDB: d6ffga2
   automated match to d4qeua_
   complexed with d7b, edo, mes, peg

Details for d6ffga1

PDB Entry: 6ffg, 1.59 Å

PDB Description: human brd2 c-terminal bromodomain with (s)-1-(2-cyclopropyl-4-(2- (hydroxymethyl)benzyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)-3,4- dihydroquinoxalin-1(2h)-yl)ethanone

PDB Compounds: (A:) Bromodomain-containing protein 2

SCOPe Domain Sequences for d6ffga1:

Sequence; same for both SEQRES and ATOM records:

>d6ffga1 a.29.2.0 (A:344-455) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gklseqlkhcngilkellskkhaayawpfykpvdasalglhdyhdiikhpmdlstvkrkm
enrdyrdaqefaadvrlmfsncykynppdhdvvamarklqdvfefryakmpd

Timeline for d6ffga1:

• d6ffga1 first appeared in SCOPe 2.07