SCOPe 2.08: Domain d6crnd1: 6crn D:280-624

Lineage for d6crnd1 (6crn D:280-624)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.0: automated matches [191342] (1 protein)
   not a true family

6. Protein automated matches [190230] (23 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187072] (53 PDB entries)

8. Domain d6crnd1: 6crn D:280-624 [362711]
   Other proteins in same PDB: d6crna2, d6crnd2, d6crne_, d6crnf_, d6crng_, d6crnh_
   automated match to d2hd5a1
   complexed with zn

Details for d6crnd1

PDB Entry: 6crn, 2.5 Å

PDB Description: structure of the usp15 deubiquitinase domain in complex with a high- affinity first-generation ubv

PDB Compounds: (D:) ubiquitin carboxyl-terminal hydrolase 15

SCOPe Domain Sequences for d6crnd1:

Sequence, based on SEQRES records:

>d6crnd1 d.3.1.0 (D:280-624) automated matches {Human (Homo sapiens) [TaxId: 9606]}
grnneqpglcglsnlgntcfmnsaiqclsntpplteyflndkyqeelnfdnplgmrgeia
ksyaelikqmwsgkfsyvtprafktqvgrfapqfsgyqqqdcqellaflldglhedlnri
rkkpyiqlkdadgrpdkvvaeeawenhlkrndsiivdifhglfkstlvcpecakisvtfd
pfcyltlplpmpkkpfvklkdcielfttkeklgaedpwycpnckehqqatkkldlwslpp
vlvvhlkrfsysrymrdkldtlvdfpindldmseflinpnagpcrynliavsnhyggmgg
ghytafaknkddgkwyyfddssvstasedqivskaayvlfyqrqd

Sequence, based on observed residues (ATOM records):

>d6crnd1 d.3.1.0 (D:280-624) automated matches {Human (Homo sapiens) [TaxId: 9606]}
grnneqpglcglsnlgntcfmnsaiqclsntpplteyflndkyqeelnfdnplgmrgeia
ksyaelikqmwsgkfsyvtprafktqvgrfapqfsqqqdcqellaflldglhedlnrirk
kpyiqlkdadgrpdkvvaeeawenhlkrndsiivdifhglfkstlvcpecakisvtfdpf
cyltlplpmpkkpfvklkdcielfttkekledpwycpnckehqqatkkldlwslppvlvv
hlkrfsysrymrdkldtlvdfpindldmseflinpnagpcrynliavsnhyggmggghyt
afaknkddgkwyyfddssvstasedqivskaayvlfyqrqd

Timeline for d6crnd1:

• d6crnd1 first appeared in SCOPe 2.07