Lineage for d6fs2a1 (6fs2 A:174-325)

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021303Protein EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212] (2 species)
  7. 3021304Species Human (Homo sapiens) [TaxId:9606] [188549] (62 PDB entries)
  8. 3021425Domain d6fs2a1: 6fs2 A:174-325 [361663]
    Other proteins in same PDB: d6fs2a2, d6fs2b2
    automated match to d2kbwa_
    complexed with e4k

Details for d6fs2a1

PDB Entry: 6fs2 (more details), 2.55 Å

PDB Description: mcl1 in complex with indole acid ligand
PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d6fs2a1:

Sequence, based on SEQRES records: (download)

>d6fs2a1 f.1.4.1 (A:174-325) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d6fs2a1 f.1.4.1 (A:174-325) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d6fs2a1:

Click to download the PDB-style file with coordinates for d6fs2a1.
(The format of our PDB-style files is described here.)

Timeline for d6fs2a1:

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