SCOPe 2.08: Domain d6mr5a_: 6mr5 A:

Lineage for d6mr5a_ (6mr5 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.0: automated matches [191435] (1 protein)
   not a true family

6. Protein automated matches [190626] (14 species)
   not a true protein

7. Species Zebrafish (Danio rerio) [TaxId:7955] [319911] (55 PDB entries)

8. Domain d6mr5a_: 6mr5 A: [360834]
   automated match to d5g0ha_
   complexed with edo, flc, k, peg, w45, zn

Details for d6mr5a_

PDB Entry: 6mr5, 1.85 Å

PDB Description: crystal structure of danio rerio histone deacetylase 6 catalytic domain 2 in complex with a mercaptoacetamide-based inhibitor

PDB Compounds: (A:) Hdac6 protein

SCOPe Domain Sequences for d6mr5a_:

Sequence, based on SEQRES records:

>d6mr5a_ c.42.1.0 (A:) automated matches {Zebrafish (Danio rerio) [TaxId: 7955]}
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwsslr

Sequence, based on observed residues (ATOM records):

>d6mr5a_ c.42.1.0 (A:) automated matches {Zebrafish (Danio rerio) [TaxId: 7955]}
pitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlateeelal
chsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqailtgqv
rnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhgngtqh
ifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdpeymaa
fhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagrvliil
eggynltsisesmsmctsmllgdsppsldtplktsatvsinnvlrahapfwsslr

Timeline for d6mr5a_:

• d6mr5a_ first appeared in SCOPe 2.07