SCOPe 2.07: Domain d6cqza_: 6cqz A:

Lineage for d6cqza_ (6cqz A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein automated matches [190065] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186857] (69 PDB entries)

8. Domain d6cqza_: 6cqz A: [360814]
   automated match to d2xupa_
   complexed with fuc, nag, vx

Details for d6cqza_

PDB Entry: 6cqz, 2.22 Å

PDB Description: crystal structure of recombinant human acetylcholinesterase inhibited by vx

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d6cqza_:

Sequence, based on SEQRES records:

>d6cqza_ c.69.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
redaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvda
ttfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiyggg
fysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqw
vqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmg
earrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpv
vdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflag
vrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqg
arvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywan
fartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

Sequence, based on observed residues (ATOM records):

>d6cqza_ c.69.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
redaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvda
ttfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiyggg
fysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqw
vqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmg
earrratqlahlvgcppggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdg
dflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrv
gvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarv
yayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfar
tgdpnepqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

Timeline for d6cqza_:

• d6cqza_ is new in SCOPe 2.07-stable
  
• d6cqza_ appears in the current release, SCOPe 2.08