SCOPe 2.08: Domain d6gucc1: 6guc C:1-296

Lineage for d6gucc1 (6guc C:1-296)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
   Uniprot P24941

8. Domain d6gucc1: 6guc C:1-296 [360786]
   Other proteins in same PDB: d6guca2, d6gucb1, d6gucb2, d6gucc2, d6gucd1, d6gucd2
   automated match to d4fkla_
   complexed with su9

Details for d6gucc1

PDB Entry: 6guc, 2 Å

PDB Description: cdk2/cyclina in complex with su9516

PDB Compounds: (C:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d6gucc1:

Sequence; same for both SEQRES and ATOM records:

>d6gucc1 d.144.1.7 (C:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d6gucc1:

• d6gucc1 first appeared in SCOPe 2.07