SCOPe 2.08: Domain d6bxha1: 6bxh A:2-230

Lineage for d6bxha1 (6bxh A:2-230)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.389: Menin N-terminal domain-like [310556] (1 superfamily)
   Some structural similarity to cysteine proteinases (d.3.1.4) noted in PubMed 22327296

4. Superfamily d.389.1: Menin N-terminal domain-like [310582] (1 family)
   Pfam PF05053

5. Family d.389.1.1: Menin N-terminal domain-like [310623] (2 proteins)

6. Protein Menin N-terminal domain [310724] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310972] (34 PDB entries)

8. Domain d6bxha1: 6bxh A:2-230 [360638]
   Other proteins in same PDB: d6bxha2, d6bxha3
   automated match to d3u84b1
   complexed with dms, ee7, so4

Details for d6bxha1

PDB Entry: 6bxh, 2.45 Å

PDB Description: menin in complex with mi-853

PDB Compounds: (A:) Menin

SCOPe Domain Sequences for d6bxha1:

Sequence, based on SEQRES records:

>d6bxha1 d.389.1.1 (A:2-230) Menin N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrviptnvpel
tfqpspapdppggltyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkv
sdviwnslsrsyfkdrahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedh
awvvfgpngeqtaevtwhgkgnedrrgqtvnagvaerswlylkgsymrc

Sequence, based on observed residues (ATOM records):

>d6bxha1 d.389.1.1 (A:2-230) Menin N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvgltyfpva
dlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfkdrahiq
slfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtaevtwhgk
gnedrrgqtvnagvaerswlylkgsymrc

Timeline for d6bxha1:

• d6bxha1 first appeared in SCOPe 2.07