SCOPe 2.08: Domain d6fina_: 6fin A:

Lineage for d6fina_ (6fin A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6fina_: 6fin A: [360602]
   automated match to d3zosa_
   complexed with djq, iod

Details for d6fina_

PDB Entry: 6fin, 1.67 Å

PDB Description: ddr1, 3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1h-indazole-5- carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 1.670a, p1211, rfree=22.8%

PDB Compounds: (A:) epithelial discoidin domain-containing receptor 1

SCOPe Domain Sequences for d6fina_:

Sequence, based on SEQRES records:

>d6fina_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpdat
knarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledka
aegapgdptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgms
rnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgql
tdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaed
aln

Sequence, based on observed residues (ATOM records):

>d6fina_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vdfprsrlrfkeklgegqfgevhlcevdspqdlvsplnvrkghpllvavkilrpdatkna
rndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledkaapt
isypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnlyagdyy
rvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqviena
geffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaedaln

Timeline for d6fina_:

• d6fina_ first appeared in SCOPe 2.07