SCOPe 2.08: Domain d6cmqc2: 6cmq C:219-528

Lineage for d6cmqc2 (6cmq C:219-528)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d6cmqc2: 6cmq C:219-528 [360208]
   Other proteins in same PDB: d6cmqa1, d6cmqb1, d6cmqc1, d6cmqd1
   automated match to d4nwga3

Details for d6cmqc2

PDB Entry: 6cmq, 2.9 Å

PDB Description: structure of human shp2 without n-sh2 domain

PDB Compounds: (C:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6cmqc2:

Sequence, based on SEQRES records:

>d6cmqc2 c.45.1.0 (C:219-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsklaettdkvkqgfweefetlqqqeckllysrkegqrqenknknr
yknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnnskpkksyiatqgclqntv
ndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkesaahdytl
relklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvh
csagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymav
qhyietlqrr

Sequence, based on observed residues (ATOM records):

>d6cmqc2 c.45.1.0 (C:219-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trinaaeiesrvrelsklgfweefetlqqqeckllysrkegqrqenknknryknilpfdh
trvvlhdgdpnepvsdyinaniimpefkpkksyiatqgclqntvndfwrmvfqensrviv
mttkevergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntert
vwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividi
lidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrr

Timeline for d6cmqc2:

• d6cmqc2 first appeared in SCOPe 2.07