SCOPe 2.08: Domain d6dv4b_: 6dv4 B:

Lineage for d6dv4b_ (6dv4 B:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (590 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d6dv4b_: 6dv4 B: [359528]
   automated match to d1sdta_
   complexed with act, cl, ga5, gol, na

Details for d6dv4b_

PDB Entry: 6dv4, 1.14 Å

PDB Description: hiv-1 wild type protease with grl-04315a, a tetrahydronaphthalene carboxamide with (r)-boc-amine and (s)-hydroxyl functionalities as the p2 ligand

PDB Compounds: (B:) Protease

SCOPe Domain Sequences for d6dv4b_:

Sequence; same for both SEQRES and ATOM records:

>d6dv4b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d6dv4b_:

• d6dv4b_ first appeared in SCOPe 2.07