Lineage for d6bazc2 (6baz C:160-331)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2998746Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 2998747Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 2998748Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 2998755Protein Lactate dehydrogenase [56339] (20 species)
  7. 2998826Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (39 PDB entries)
  8. 2998999Domain d6bazc2: 6baz C:160-331 [359125]
    Other proteins in same PDB: d6baza1, d6bazb1, d6bazc1, d6bazd1
    automated match to d1i10d2
    complexed with d47, epe, lac, nad, so4

Details for d6bazc2

PDB Entry: 6baz (more details), 2.7 Å

PDB Description: lactate dehydrogenase in complex with inhibitor (s)-5-((2- chlorophenyl)thio)-6'-((4-fluorophenyl)amino)-4-hydroxy-2-(thiophen- 3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1h)-one
PDB Compounds: (C:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d6bazc2:

Sequence; same for both SEQRES and ATOM records: (download)

>d6bazc2 d.162.1.1 (C:160-331) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
sgcnldsarfrylmgerlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgt
dkdkeqwkevhkqvvesayeviklkgytswaiglsvadlaesimknlrrvhpvstmikgl
ygikddvflsvpcilgqngisdlvkvtltseeearlkksadtlwgiqkelqf

SCOPe Domain Coordinates for d6bazc2:

Click to download the PDB-style file with coordinates for d6bazc2.
(The format of our PDB-style files is described here.)

Timeline for d6bazc2: