Lineage for d5yavb_ (5yav B:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2361840Superfamily b.1.18: E set domains [81296] (24 families) (S)
    "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
  5. 2362347Family b.1.18.8: RhoGDI-like [81288] (3 proteins)
  6. 2362348Protein GMP-PDE delta [74846] (1 species)
  7. 2362349Species Human (Homo sapiens) [TaxId:9606] [74847] (25 PDB entries)
  8. 3057058Domain d5yavb_: 5yav B: [357120]
    automated match to d5x72a_
    complexed with 8sf

Details for d5yavb_

PDB Entry: 5yav (more details), 1.99 Å

PDB Description: fragment-based drug discovery of inhibitors to block pdedelta-ras protein-protein interaction
PDB Compounds: (B:) Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

SCOPe Domain Sequences for d5yavb_:

Sequence, based on SEQRES records: (download)

>d5yavb_ b.1.18.8 (B:) GMP-PDE delta {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d5yavb_ b.1.18.8 (B:) GMP-PDE delta {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5yavb_:

Click to download the PDB-style file with coordinates for d5yavb_.
(The format of our PDB-style files is described here.)

Timeline for d5yavb_:

  • d5yavb_ is new in SCOPe 2.07-stable