Lineage for d6c56a1 (6c56 A:1-295)

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)
  6. Protein Geranylgeranyl pyrophosphate synthetase [158813] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [158814] (5 PDB entries)
    Uniprot O95749 6-296
  8. Domain d6c56a1: 6c56 A:1-295 [357013]
    Other proteins in same PDB: d6c56a2, d6c56b2
    automated match to d2q80a1
    complexed with vt0; mutant

Details for d6c56a1

PDB Entry: 6c56 (more details), 2.8 Å

PDB Description: crystal structure of mutant human geranylgeranyl pyrophosphate synthase (y246d) in its apo form
PDB Compounds: (A:) Geranylgeranyl pyrophosphate synthase

SCOPe Domain Sequences for d6c56a1:

Sequence, based on SEQRES records: (download)

>d6c56a1 a.128.1.1 (A:1-295) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
mektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnas
lliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqll
elhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntl
glffqirddyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqnilrqrten
idikkdcvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

Sequence, based on observed residues (ATOM records): (download)

>d6c56a1 a.128.1.1 (A:1-295) Geranylgeranyl pyrophosphate synthetase {Human (Homo sapiens) [TaxId: 9606]}
mektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnas
lliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhpdavklftrqll
elhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntl
glffqirddyanlhsnksfcedltegkfsfptihaiwsrilrqrtenidikkdcvhyled
vgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

SCOPe Domain Coordinates for d6c56a1 are not available.

Timeline for d6c56a1:

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Domains from same chain:
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d6c56a2
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Domains from other chains:
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d6c56b1, d6c56b2