Lineage for d6aaja_ (6aaj A:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. Protein automated matches [190417] (36 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1454 PDB entries)
  8. Domain d6aaja_: 6aaj A: [356112]
    automated match to d4jiaa_
    complexed with 9t6

Details for d6aaja_

PDB Entry: 6aaj (more details), 2.3699999999999997 Å

PDB Description: crystal structure of jak2 in complex with peficitinib
PDB Compounds: (A:) Tyrosine-protein kinase JAK2

SCOPe Domain Sequences for d6aaja_:

Sequence, based on SEQRES records: (download)

>d6aaja_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysagrrnlklimeylpygslrdylqahaeridhikllqytsqick
gmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwya
peslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliell
knngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnm

Sequence, based on observed residues (ATOM records): (download)

>d6aaja_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqsteehlrdfereieilk
slqhdnivkykgvcysnlklimeylpygslrdylqahaeridhikllqytsqickgmeyl
gtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwyapeslt
eskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliellknngr
lprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnm

SCOPe Domain Coordinates for d6aaja_ are not available.

Timeline for d6aaja_:

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Domains from other chains:
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d6aajb_