SCOPe 2.08: Domain d5nrnb_: 5nrn B:

Lineage for d5nrnb_ (5nrn B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:83332] [346929] (5 PDB entries)

8. Domain d5nrnb_: 5nrn B: [355956]
   automated match to d1gsia_
   complexed with 95w, cl

Details for d5nrnb_

PDB Entry: 5nrn, 2.2 Å

PDB Description: mtb tmk crystal structure in complex with compound 3

PDB Compounds: (B:) thymidylate kinase

SCOPe Domain Sequences for d5nrnb_:

Sequence; same for both SEQRES and ATOM records:

>d5nrnb_ c.37.1.1 (B:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 83332]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatlappd

Timeline for d5nrnb_:

• d5nrnb_ first appeared in SCOPe 2.07