SCOPe 2.08: Domain d6emhc_: 6emh C:

Lineage for d6emhc_ (6emh C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56138] (50 PDB entries)

8. Domain d6emhc_: 6emh C: [355828]
   automated match to d3elja_
   complexed with bge, bme, c15, cl, edo, gol, peg

Details for d6emhc_

PDB Entry: 6emh, 1.76 Å

PDB Description: crystal structure of jnk3 in complex with a pyridinylimidazole inhibitor

PDB Compounds: (C:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d6emhc_:

Sequence, based on SEQRES records:

>d6emhc_ d.144.1.7 (C:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmn

Sequence, based on observed residues (ATOM records):

>d6emhc_ d.144.1.7 (C:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigivcaaydavldrnvaikklsrpfqnqthakrayr
elvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyll
yqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartavtryyrapevilgmgy
kenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyven
rpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyin
vwydpaeveapppqiydehtieewkeliykevmn

Timeline for d6emhc_:

• d6emhc_ first appeared in SCOPe 2.07