SCOPe 2.08: Domain d6g3ub_: 6g3u B:

Lineage for d6g3ub_ (6g3u B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (2 proteins)
   the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion
   automatically mapped to Pfam PF03971

6. Protein automated matches [190493] (6 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:287] [355639] (1 PDB entry)

8. Domain d6g3ub_: 6g3u B: [355645]
   automated match to d2b0ta_
   complexed with akg, nap

Details for d6g3ub_

PDB Entry: 6g3u, 2.71 Å

PDB Description: structure of pseudomonas aeruginosa isocitrate dehydrogenase, idh

PDB Compounds: (B:) isocitrate dehydrogenase

SCOPe Domain Sequences for d6g3ub_:

Sequence, based on SEQRES records:

>d6g3ub_ c.77.1.2 (B:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}
skitytftdeapalatysllpivkafaasagidvetsdislagrilanfadrleadqrie
ddlarlavlatspdaniiklpnisasvpqlkgaiaelqglgykvpdfpedpqtdeekevr
aryakilgsavnpvlregnsdrrapaavkayarkhphsmgkwsmasrshadymrggdffs
seqsitmakagdvriefvgkdgkvevkkqlslqegevldsmfmscgklrdffektlqdck
etgvmwslhvkatmmkishpivfghavsvyykdvfdkwgqlfeelgvnpnngissvydki
kslpasqqeeilhdihevyshrpemamvdsvkgitnlhipsdvivdasmpamirnsgqmw
gkdgkqkdtkavmpestyariyqeminfcktngafdpttmgsvpnvglmaqkaeeygshd
ktfemtadgtmrvvladgsvlmqhkvetgdiwracqtkdapirdwvklavtrarqsdtpa
ifwldperahdrelrkkvelylkdhdltgldisimgyneairvsmerlirgkdtisvtgn
vlrdyltdlfpimelgtsakmlsivplmagggmyetgaggsapkhvqqlveenylrwdsl
geflalavsleetgiktgnakakllgkaldeatgklldnnkspsrkvgdidnrgshfyla
mywaqalaaqnedaelkahfaplakalteqeativaelnavqgkpaeiggyyrsnpelts
kvmrpsatfnaaidsl

Sequence, based on observed residues (ATOM records):

>d6g3ub_ c.77.1.2 (B:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}
skitytftdeapalatysllpivkafaasagidvetsdislagrilanfadrleadqrie
ddlarlavlatspdaniiklpnisasvpqlkgaiaelqglgykvpdfpedpqtdeekevr
aryakilgsavnpvlregnsdrrapaavkayarkhphsmgkwsmasrshadymrggdffs
seqsitmakagdvriefvgkdgkvevkkqlslqegevldsmfmscgklrdffektlqdck
etgvmwslhvkatmmkishpivfghavsvyykdvfdkwgqlfeelgvnpnngissvydki
kslpasqqeeilhdihevyshrpemamvdsvkgitnlhipsdvivdasmpamirnsgqmw
gkdgkqkdtkavmpestyariyqeminfcktngafdpttmgsvpnvglmaqkaeeygshd
ktfemtadgtmrvvladgsvlmqhkvetgdiwracqtkdapirdwvklavtrarqsdtpa
ifwldperahdrelrkkvelylkdhdltgldisimgyneairvsmerlirgkdtisvtgn
vlrdyltdlfpimelgtsakmlsivplmagggmyetgaggsapkhvqqlrwdslgeflal
avsleetgiktgnakakllgkaldeatgklldnnkspsrkvgdidnrgshfylamywaqa
laaqnedaelkahfaplakalteqeativaelnavqgkpaeiggyyrsnpeltskvmrps
atfnaaidsl

Timeline for d6g3ub_:

• d6g3ub_ first appeared in SCOPe 2.07