Lineage for d2gpaa_ (2gpa A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2142044Fold c.87: UDP-Glycosyltransferase/glycogen phosphorylase [53755] (1 superfamily)
    consists of two non-similar domains with 3 layers (a/b/a) each
    domain 1: parallel beta-sheet of 7 strands, order 3214567
    domain 2: parallel beta-sheet of 6 strands, order 321456
  4. 2142045Superfamily c.87.1: UDP-Glycosyltransferase/glycogen phosphorylase [53756] (14 families) (S)
  5. 2142109Family c.87.1.4: Oligosaccharide phosphorylase [53766] (3 protein domains)
    automatically mapped to Pfam PF00343
  6. 2142110Protein Glycogen phosphorylase [53767] (3 species)
    both domains are elaborated with many insertions
  7. 2142145Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53769] (74 PDB entries)
    Uniprot P00489 ! Uniprot P00489
  8. 2142152Domain d2gpaa_: 2gpa A: [35493]
    complexed with glc, gol, plp

Details for d2gpaa_

PDB Entry: 2gpa (more details), 2 Å

PDB Description: allosteric inhibition of glycogen phosphorylase a by a potential antidiabetic drug
PDB Compounds: (A:) protein (glycogen phosphorylase)

SCOPe Domain Sequences for d2gpaa_:

Sequence, based on SEQRES records: (download)

>d2gpaa_ c.87.1.4 (A:) Glycogen phosphorylase {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
sdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlv
grwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeelee
ieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlr
ygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlw
sakapndfnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatl
qdiirrfksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerldwdka
wevtvktcaytnhtvlpealerwpvhlletllprhlqiiyeinqrflnrvaaafpgdvdr
lrrmslveegavkrinmahlciagshavngvarihseilkktifkdfyelephkfqnktn
gitprrwlvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqenklk
faaylereykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvprtvm
iggkaapgyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaadlse
qistagteasgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdrldqr
gynaqeyydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcq
ervsalyknprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpapd

Sequence, based on observed residues (ATOM records): (download)

>d2gpaa_ c.87.1.4 (A:) Glycogen phosphorylase {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
sdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlv
grwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeelee
ieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlr
ygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlw
sakapngyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksn
fdafpdkvaiqlndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvlpeale
rwpvhlletllprhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinmahlc
iagshavngvarihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaeiiae
rigeeyisdldqlrkllsyvddeafirdvakvkqenklkfaaylereykvhinpnslfdv
qvkriheykrqllnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiiklita
igdvvnhdpvvgdrlrviflenyrvslaekvipaadlseqistagteasgtgnmkfmlng
altigtmdganvemaeeageenffifgmrvedvdrldqrgynaqeyydripelrqiieql
ssgffspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvirni
atsgkfssdrtiaqyareiwgvepsrqrlpapd

SCOPe Domain Coordinates for d2gpaa_:

Click to download the PDB-style file with coordinates for d2gpaa_.
(The format of our PDB-style files is described here.)

Timeline for d2gpaa_: