Lineage for d5utzi_ (5utz I:)

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. Protein Interleukin-2 (IL-2) [47301] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [47302] (19 PDB entries)
  8. Domain d5utzi_: 5utz I: [354776]
    Other proteins in same PDB: d5utzb_, d5utzc1, d5utzc2, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2
    automated match to d1m48b_
    complexed with gol

Details for d5utzi_

PDB Entry: 5utz (more details), 2.75 Å

PDB Description: human il-2/fab complex
PDB Compounds: (I:) interleukin-2

SCOPe Domain Sequences for d5utzi_:

Sequence, based on SEQRES records: (download)

>d5utzi_ a.26.1.2 (I:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwit
fcqsiistlt

Sequence, based on observed residues (ATOM records): (download)

>d5utzi_ a.26.1.2 (I:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleevlnlaqsknfhlrprdlisninvivlelkgfmceyadetativeflnrwitfcqs
iistlt

SCOPe Domain Coordinates for d5utzi_ are not available.

Timeline for d5utzi_:

Domains from other chains:
(mouse over for more information)
d5utza_, d5utzb_, d5utzc1, d5utzc2, d5utzd_, d5utze_, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2