SCOPe 2.08: Domain d6glbb_: 6glb B:

Lineage for d6glbb_ (6glb B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6glbb_: 6glb B: [354177]
   automated match to d1yvja_
   complexed with edo, f48, phu

Details for d6glbb_

PDB Entry: 6glb, 2 Å

PDB Description: crystal structure of jak3 in complex with compound 20 (fm484)

PDB Compounds: (B:) Tyrosine-protein kinase JAK3

SCOPe Domain Sequences for d6glbb_:

Sequence, based on SEQRES records:

>d6glbb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqrei
qilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssq
ickgmeylgsrrcvhralaarnilveseahvkiadfglakllpldkdyyvvrepgqspif
wyapeslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrlle
lleegqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlwsgsr

Sequence, based on observed residues (ATOM records):

>d6glbb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqrei
qilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssq
ickgmeylgsrrcvhralaarnilveseahvkiadfglakllpldkdyyvvrqspifwya
peslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrllelle
egqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlwsgsr

Timeline for d6glbb_:

• d6glbb_ first appeared in SCOPe 2.07