SCOPe 2.07: Domain d6cr2b1: 6cr2 B:51-518

Lineage for d6cr2b1 (6cr2 B:51-518)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (95 species)
   not a true protein

7. Species Aspergillus fumigatus [TaxId:330879] [353881] (1 PDB entry)

8. Domain d6cr2b1: 6cr2 B:51-518 [353882]
   Other proteins in same PDB: d6cr2a2, d6cr2b2
   automated match to d3zg2a_
   complexed with hem, lfv

Details for d6cr2b1

PDB Entry: 6cr2, 2.38 Å

PDB Description: crystal structure of sterol 14-alpha demethylase (cyp51b) from aspergillus fumigatus in complex with the vni derivative n-(1-(2,4- dichlorophenyl)-2-(1h-imidazol-1-yl)ethyl)-4-(5-(2-fluoro-4-(2,2,2- trifluoroethoxy)phenyl)-1,3,4-oxadiazol-2-yl)benzamide

PDB Compounds: (B:) 14-alpha sterol demethylase Cyp51B

SCOPe Domain Sequences for d6cr2b1:

Sequence; same for both SEQRES and ATOM records:

>d6cr2b1 a.104.1.0 (B:51-518) automated matches {Aspergillus fumigatus [TaxId: 330879]}
tppvvfhwfpfigstisygidpykfffdcrakygdiftfillgkkttvylgtkgndfiln
gklrdvcaeevysplttpvfgrhvvydcpnaklmeqkkfvkygltsdalrsyvplitdev
esfvknspafqghkgvfdvcktiaeitiytasrslqgkevrskfdstfaelyhnldmgfa
pinfmlpwaplphnrkrdaaqrkltetymeiikarrqagskkdsedmvwnlmscvykngt
pvpdeeiahmmiallmagqhsssstaswivlrlatrpdimeelyqeqirvlgsdlpplty
dnlqkldlhakviketlrlhapihsiiravknpmavdgtsyviptshnvlsspgvtarse
ehfpnplewnphrwdeniaasaeddekvdygyglvskgtnspylpfgagrhrcigeqfay
lqlgtitavlvrlfrfrnlpgvdgipdtdysslfskplgrsfvefekr

Timeline for d6cr2b1:

• d6cr2b1 is new in SCOPe 2.07-stable
  
• d6cr2b1 appears in the current release, SCOPe 2.08