Lineage for d5ylta2 (5ylt A:194-364)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2817864Fold b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  4. 2818606Superfamily b.85.7: SET domain [82199] (4 families) (S)
    duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
    also contains a substrate-binding alpha+beta subdomain inserted in the core
    Pfam PF00856
  5. 2818607Family b.85.7.1: Histone lysine methyltransferases [82200] (3 proteins)
    contains metal-binding preSET (Pfam PF05033) or AWS (Associated With SET, Pfam PF17907), and postSET domains
  6. 2818613Protein Histone H3 K4-specific methyltransferase SET7/9 catalytic domain [82205] (1 species)
  7. 2818614Species Human (Homo sapiens) [TaxId:9606] [82206] (19 PDB entries)
    Uniprot Q8WTS6 52-336
  8. 2818624Domain d5ylta2: 5ylt A:194-364 [353787]
    Other proteins in same PDB: d5ylta1
    automated match to d4jdsa2
    complexed with c7n, gol, sfg

Details for d5ylta2

PDB Entry: 5ylt (more details), 1.69 Å

PDB Description: crystal structure of set7/9 in complex with a cyproheptadine derivative
PDB Compounds: (A:) Histone-lysine N-methyltransferase SETD7

SCOPe Domain Sequences for d5ylta2:

Sequence, based on SEQRES records: (download)

>d5ylta2 b.85.7.1 (A:194-364) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydhsppgksgpeapewyqvelkafqatq

Sequence, based on observed residues (ATOM records): (download)

>d5ylta2 b.85.7.1 (A:194-364) Histone H3 K4-specific methyltransferase SET7/9 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
dkstsscistnallpdpyeservyvaeslissageglfskvavgpntvmsfyngvrithq
evdsrdwalngntlsldeetvidvpepynhvskycaslghkanhsftpnciydmfvhprf
gpikcirtlraveadeeltvaygydhsppgksapewyqvelkafqatq

SCOPe Domain Coordinates for d5ylta2:

Click to download the PDB-style file with coordinates for d5ylta2.
(The format of our PDB-style files is described here.)

Timeline for d5ylta2:

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Domains from same chain:
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d5ylta1