SCOPe 2.05: Domain d1c7ra_: 1c7r A:

Lineage for d1c7ra_ (1c7r A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.80: SIS domain [53696] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.80.1: SIS domain [53697] (4 families)

5. Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (2 proteins)
   permutation of the double-SIS domain fold
   automatically mapped to Pfam PF00342

6. Protein Phosphoglucose isomerase, PGI [53702] (7 species)
   moonlights as neuroleukin, autocrine motility factor, and differentiation mediator

7. Species Bacillus stearothermophilus [TaxId:1422] [53704] (4 PDB entries)

8. Domain d1c7ra_: 1c7r A: [35310]
   complexed with pa5

Details for d1c7ra_

PDB Entry: 1c7r, 2.5 Å

PDB Description: the crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors and its substrate recognition mechanism

PDB Compounds: (A:) phosphoglucose isomerase

SCOPe Domain Sequences for d1c7ra_:

Sequence, based on SEQRES records:

>d1c7ra_ c.80.1.2 (A:) Phosphoglucose isomerase, PGI {Bacillus stearothermophilus [TaxId: 1422]}
aisfdysnalpfmqeneldylsefvkaahhmlherkgpgsdflgwvdwpirydknefsri
kqaaerirnhsdalvvigiggsylgaraaiealshtfhnqmndttqiyfagqnisstyis
hlldvlegkdlsinvisksgtttepaiafrifrdymekkygkeearkriyvttdrtkgal
kkladqegyetfvipdniggrysvltavgllpiavaglnidrmmegaasayhkynnpdll
tnesyqyaavrnilyrkgkaiellvnyepslhyvsewwkqlfgesegkdqkglfpasvdf
ttdlhsmgqyvqegrrnlietvlhvkkpqieltiqedpenidglnflagktldevnkkaf
qgtllahvdggvpnliveldemneytfgemvyffekacgisghllgvnpfdqpgveaykk
nmfallgkpgfedekaalmkrl

Sequence, based on observed residues (ATOM records):

>d1c7ra_ c.80.1.2 (A:) Phosphoglucose isomerase, PGI {Bacillus stearothermophilus [TaxId: 1422]}
aisfdysnalpfmqeneldylsefvkaahhmlherkgpgsdflgwvdwpirydknefsri
kqaaerirnhsdalvvigiggsylgaraaiealstqiyfagqnisstyishlldvlegkd
lsinvisksgtttepaiafrifrdymekkygkeearkriyvttdrtkgalkkladqegye
tfvipdniggrysvltavgllpiavaglnidrmmegaasayhkynnpdlltnesyqyaav
rnilyrkgkaiellvnyepslhyvsewwkqlfgesegkdqkglfpasvdfttdlhsmgqy
vqegrrnlietvlhvkkpqieltiqedpenidglnflagktldevnkkafqgtllahvdg
gvpnliveldemneytfgemvyffekacgisghllgvnpfdqpgveaykknmfallgkpg
fedekaalmkrl

Timeline for d1c7ra_:

• d1c7ra_ first appeared (with stable ids) in SCOP 1.55
  
• d1c7ra_ appears in SCOPe 2.04
  
• d1c7ra_ appears in SCOPe 2.06
  
• d1c7ra_ appears in the current release, SCOPe 2.08