Lineage for d6gina_ (6gin A:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. Protein automated matches [190091] (20 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [188447] (844 PDB entries)
  8. Domain d6gina_: 6gin A: [352614]
    automated match to d6eixa_
    complexed with edo, ir2, so4

Details for d6gina_

PDB Entry: 6gin (more details), 2.2 Å

PDB Description: crystal structure of the acvr1 (alk2) kinase in complex with an quinazolinone based alk2 inhibitor with a 4-morpholinophenyl solvent accessible group.
PDB Compounds: (A:) Activin receptor type-1

SCOPe Domain Sequences for d6gina_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6gina_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
varditllecvgkgrygevwrgswqgenvavkifssrdekswfretelyntvmlrhenil
gfiasdmtsrhsstqlwlithyhemgslydylqlttldtvsclrivlsiasglahlhiei
fgtqgkpaiahrdlksknilvkkngqcciadlglavmhsqstnqldvgnnprvgtkryma
pevldetiqvdcfdsykrvdiwafglvlwevarrmvsngivedykppfydvvpndpsfed
mrkvvcvdqqrpnipnrwfsdptltslaklmkecwyqnpsarltalrikktltkid

SCOPe Domain Coordinates for d6gina_ are not available.

Timeline for d6gina_:

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Domains from other chains:
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d6ginb_