Lineage for d5xsub2 (5xsu B:136-349)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 3000428Fold d.166: ADP-ribosylation [56398] (1 superfamily)
    unusual fold
  4. 3000429Superfamily d.166.1: ADP-ribosylation [56399] (8 families) (S)
  5. 3000733Family d.166.1.0: automated matches [191650] (1 protein)
    not a true family
  6. 3000734Protein automated matches [191197] (13 species)
    not a true protein
  7. 3000809Species Human (Homo sapiens) [TaxId:9606] [225406] (55 PDB entries)
  8. 3000896Domain d5xsub2: 5xsu B:136-349 [351570]
    Other proteins in same PDB: d5xsua1, d5xsub1, d5xsuc1, d5xsud1
    automated match to d4hhyd2
    complexed with 8e3, so4

Details for d5xsub2

PDB Entry: 5xsu (more details), 2.4 Å

PDB Description: novel orally efficacious inhibitors complexed with parp1
PDB Compounds: (B:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5xsub2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5xsub2 d.166.1.0 (B:136-349) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lktdikvvdrdseeaeiirkyvknthatthnaydlevidifkieregecqrykpfkqlhn
rrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvsksanychtsqgdpi
glillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsanisldgvdvplgtgis
sgvndtsllyneyivydiaqvnlkyllklkfnfk

SCOPe Domain Coordinates for d5xsub2:

Click to download the PDB-style file with coordinates for d5xsub2.
(The format of our PDB-style files is described here.)

Timeline for d5xsub2: