Lineage for d6cmmc_ (6cmm C:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. Protein automated matches [190417] (36 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1454 PDB entries)
  8. Domain d6cmmc_: 6cmm C: [350786]
    automated match to d6bu6a_
    complexed with act, f7d, peg, so4

Details for d6cmmc_

PDB Entry: 6cmm (more details), 2.1 Å

PDB Description: crystal structure of the human vaccinia-related kinase bound to a n,n- dipropynyl-dihydropteridine inhibitor
PDB Compounds: (C:) Serine/threonine-protein kinase VRK1

SCOPe Domain Sequences for d6cmmc_:

Sequence, based on SEQRES records: (download)

>d6cmmc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eqfavgeiitdmaaaawkvglpigqggfgciyladmnssesvgsdapcvvkvepsdngpl
ftelkfyqraakpeqiqkwirtrklkylgvpkywgsglhdkngksyrfmimdrfgsdlqk
iyeanakrfsrktvlqlslrildileyiheheyvhgdikasnlllnyknpdqvylvdygl
ayrycpegvhkayaadpkrchdgtieftsidahngvapsrrgdleilgycmiqwltghlp
wednlkdpkyvrdskiryreniaslmdkcfpaanapgeiakymetvklldytekplyenl
rdillqglkaigskddgkldl

Sequence, based on observed residues (ATOM records): (download)

>d6cmmc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eqfavgeiitdmaaaawkvglpigciyladmnssesvgsdapcvvkvepsdngplftelk
fyqraakpeqiqkwirtrklkylgvpkywgsglhdkngksyrfmimdrfgsdlqkiyean
akrfsrktvlqlslrildileyiheheyvhgdikasnlllnyknpdqvylvdyglayryc
pegvhkayaadpkrchdgtieftsidahngvapsrrgdleilgycmiqwltghlpwednl
kdpkyvrdskiryreniaslmdkcfpaanapgeiakymetvklldytekplyenlrdill
qglkaigskddgkldl

SCOPe Domain Coordinates for d6cmmc_ are not available.

Timeline for d6cmmc_:

View in 3D
Domains from other chains:
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d6cmma_, d6cmmb_, d6cmmd_