Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.92: Zincin-like [55485] (2 superfamilies) contains mixed beta sheet with connection over free side of the sheet |
Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families) |
Family d.92.1.5: Neurolysin-like [55505] (5 proteins) combines M2, M3 and M32 families of metalloproteases the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain |
Protein Angiotensin converting enzyme, ACE [82733] (2 species) M2 family member; overall fold is similar to that of neurolysin but is less elaborated |
Species Human (Homo sapiens) [TaxId:9606] [82734] (17 PDB entries) Uniprot P22966 |
Domain d6f9ta_: 6f9t A: [350680] automated match to d4c2oa_ complexed with bo3, cl, d0z, edo, imd, peg, pge, zn |
PDB Entry: 6f9t (more details), 1.6 Å
SCOPe Domain Sequences for d6f9ta_:
Sequence; same for both SEQRES and ATOM records: (download)
>d6f9ta_ d.92.1.5 (A:) Angiotensin converting enzyme, ACE {Human (Homo sapiens) [TaxId: 9606]} deaeaskfveeydrtsqvvwneyaganwnyntnittetskillqknmqiaqhtlkygtqa rkfdvnqlqnttikriikkvqdleraalpaqeleeynkilldmettysvatvchpqgscl qlepdltnvmatsrkyedllwawegwrdkagrailqfypkyvelinqaarlngyvdagds wrsmyetpsleqdlerlfqelqplylnlhayvrralhrhygaqhinlegpipahllgnmw aqtwsniydlvvpfpsapsmdtteamlkqgwtprrmfkeaddfftslgllpvppefwqks mlekptdgrevvchasawdfyngkdfrikqcttvnledlvvahhemghiqyfmqykdlpv alreganpgfheaigdvlalsvstpkhlhslnllsseggsdehdinflmkmaldkiafip fsylvdqwrwrvfdgsitkenynqewwslrlkyqglcppvprtqgdfdpgakfhipssvp yiryfvsfiiqfqfhealcqaaghtgplhkcdiyqskeagqrlatamklgfsrpwpeamq litgqpqmsasamlsyfkplldwlrtenelhgeklgwpqynwtpns
Timeline for d6f9ta_: