SCOP 1.63: Domain d1dr8b_: 1dr8 B:

Lineage for d1dr8b_ (1dr8 B:)

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenases [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudodyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases [53659] (2 families)

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
   the active site is between the two identical subunits

6. Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (6 species)

7. Species Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)

8. Domain d1dr8b_: 1dr8 B: [35052]

Details for d1dr8b_

PDB Entry: 1dr8, 2.7 Å

PDB Description: structure of modified 3-isopropylmalate dehydrogenase at the c-terminus, hd177

SCOP Domain Sequences for d1dr8b_:

Sequence; same for both SEQRES and ATOM records:

>d1dr8b_ c.77.1.1 (B:) 3-isopropylmalate dehydrogenase, IPMDH {Thermus thermophilus}
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafelarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvgmgi

Timeline for d1dr8b_:

• d1dr8b_ first appeared (with stable ids) in SCOP 1.55
  
• d1dr8b_ appears in SCOP 1.61
  
• d1dr8b_ appears in SCOP 1.65
  
• d1dr8b_ appears in the current release, SCOPe 2.08