SCOPe 2.08: Domain d6enqb_: 6enq B:

Lineage for d6enqb_ (6enq B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d6enqb_: 6enq B: [350324]
   automated match to d1nyxa_
   complexed with bjb

Details for d6enqb_

PDB Entry: 6enq, 2.2 Å

PDB Description: structure of human ppar gamma lbd in complex with lanifibranor (iva337)

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d6enqb_:

Sequence, based on SEQRES records:

>d6enqb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d6enqb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtspfviydmnslmmgeevairifqgcqfr
sveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfm
treflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpied
iqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpl
lqeiykd

Timeline for d6enqb_:

• d6enqb_ first appeared in SCOPe 2.07