SCOPe 2.08: Domain d6bmua1: 6bmu A:3-110

Lineage for d6bmua1 (6bmu A:3-110)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.0: automated matches [191409] (1 protein)
   not a true family

6. Protein automated matches [190561] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187549] (77 PDB entries)

8. Domain d6bmua1: 6bmu A:3-110 [349763]
   Other proteins in same PDB: d6bmua3, d6bmub3
   automated match to d2shpa2
   complexed with 5od, dzv, gol, po4

Details for d6bmua1

PDB Entry: 6bmu, 2.12 Å

PDB Description: non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp244

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d6bmua1:

Sequence, based on SEQRES records:

>d6bmua1 d.93.1.0 (A:3-110) automated matches {Human (Homo sapiens) [TaxId: 9606]}
srrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntgdy
ydlyggekfatlaelvqyymehhgqlkekngdvielkyplncadptse

Sequence, based on observed residues (ATOM records):

>d6bmua1 d.93.1.0 (A:3-110) automated matches {Human (Homo sapiens) [TaxId: 9606]}
srrwfhpnitgveaenllltrgvdgsflarpsnpgdftlsvrrngavthikiqntgdyyd
lyggekfatlaelvqyymehhgqlkgdvielkyplncadptse

Timeline for d6bmua1:

• d6bmua1 first appeared in SCOPe 2.07