SCOPe 2.08: Domain d6apub_: 6apu B:

Lineage for d6apub_ (6apu B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine PRTase [53286] (4 species)

7. Species Trypanosoma brucei [TaxId:5702] [324926] (10 PDB entries)

8. Domain d6apub_: 6apu B: [349458]
   automated match to d1p17b_
   complexed with 3l6, mg, peg, so4

Details for d6apub_

PDB Entry: 6apu, 1.84 Å

PDB Description: crystal structure of trypanosoma brucei hypoxanthine-guanine phosphoribosyltranferase in complex with (2-{[2-(2-amino-6-oxo-1,6- dihydro-9h-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic acid

PDB Compounds: (B:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d6apub_:

Sequence, based on SEQRES records:

>d6apub_ c.61.1.1 (B:) Hypoxanthine PRTase {Trypanosoma brucei [TaxId: 5702]}
ackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadm
vrilgdfgvptrveflrassyghdtkscgrvdvkadglcdirgkhvlvledildtaltlr
evvdslkksepasiktlvaidkpggrkipftaeyvvadvpnvfvvgygldydqsyrevrd
vvilkpsvyetwgkelerr

Sequence, based on observed residues (ATOM records):

>d6apub_ c.61.1.1 (B:) Hypoxanthine PRTase {Trypanosoma brucei [TaxId: 5702]}
ackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadm
vrilgdfgvptrveflrdirgkhvlvledildtaltlrevvdslkksepasiktlvaidk
pggrkipftaeyvvadvpnvfvvgygldydqsyrevrdvvilkpsvyetwgkelerr

Timeline for d6apub_:

• d6apub_ first appeared in SCOPe 2.07