Lineage for d2cd2a_ (2cd2 A:)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 843142Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 843143Superfamily c.71.1: Dihydrofolate reductase-like [53597] (2 families) (S)
  5. 843144Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)
  6. 843259Protein Dihydrofolate reductases, eukaryotic type [53605] (4 species)
  7. 843269Species Fungus (Pneumocystis carinii) [TaxId:4754] [53608] (14 PDB entries)
  8. 843274Domain d2cd2a_: 2cd2 A: [34918]
    complexed with fol, nap

Details for d2cd2a_

PDB Entry: 2cd2 (more details), 1.9 Å

PDB Description: ligand induced conformational changes in the crystal structures of pneumocystis carinii dihydrofolate reductase complexes with folate and nadp+
PDB Compounds: (A:) dihydrofolate reductase

SCOP Domain Sequences for d2cd2a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2cd2a_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Fungus (Pneumocystis carinii) [TaxId: 4754]}
mnqqksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrk
twesiplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinri
fviggaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdlesw
vgtkvphgkinedgfdyefemwtrdl

SCOP Domain Coordinates for d2cd2a_:

Click to download the PDB-style file with coordinates for d2cd2a_.
(The format of our PDB-style files is described here.)

Timeline for d2cd2a_: