Lineage for d1dhfa_ (1dhf A:)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 707730Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 707731Superfamily c.71.1: Dihydrofolate reductase-like [53597] (2 families) (S)
  5. 707732Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)
  6. 707842Protein Dihydrofolate reductases, eukaryotic type [53605] (4 species)
  7. 707867Species Human (Homo sapiens) [TaxId:9606] [53607] (25 PDB entries)
  8. 707879Domain d1dhfa_: 1dhf A: [34910]

Details for d1dhfa_

PDB Entry: 1dhf (more details), 2.3 Å

PDB Description: crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazofolate
PDB Compounds: (A:) dihydrofolate reductase

SCOP Domain Sequences for d1dhfa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1dhfa_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
lncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsipek
nrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssvyke
amnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfevye
kn

SCOP Domain Coordinates for d1dhfa_:

Click to download the PDB-style file with coordinates for d1dhfa_.
(The format of our PDB-style files is described here.)

Timeline for d1dhfa_: