SCOPe 2.08: Domain d5xoda1: 5xod A:262-456

Lineage for d5xoda1 (5xod A:262-456)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
   sandwich; 11 strands in 2 sheets; greek-key

4. Superfamily b.26.1: SMAD/FHA domain [49879] (5 families)
   has a few short helices inserted in loops

5. Family b.26.1.1: SMAD domain [49880] (5 proteins)

6. Protein Smad2 MH2 domain [49883] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49884] (5 PDB entries)

8. Domain d5xoda1: 5xod A:262-456 [348828]
   Other proteins in same PDB: d5xoda2
   automated match to d1mk2a_

Details for d5xoda1

PDB Entry: 5xod, 1.85 Å

PDB Description: crystal structure of human smad2-ski complex

PDB Compounds: (A:) Mothers against decapentaplegic homolog 2

SCOPe Domain Sequences for d5xoda1:

Sequence, based on SEQRES records:

>d5xoda1 b.26.1.1 (A:262-456) Smad2 MH2 domain {Human (Homo sapiens) [TaxId: 9606]}
dlqpvtysepafwcsiayyelnqrvgetfhasqpsltvdgftdpsnserfclgllsnvnr
natvemtrrhigrgvrlyyiggevfaeclsdsaifvqspncnqrygwhpatvckippgcn
lkifnnqefaallaqsvnqgfeavyqltrmctirmsfvkgwgaeyrrqtvtstpcwielh
lngplqwldkvltqm

Sequence, based on observed residues (ATOM records):

>d5xoda1 b.26.1.1 (A:262-456) Smad2 MH2 domain {Human (Homo sapiens) [TaxId: 9606]}
dlqpvtysepafwcsiayyelnqrvgetfhasqpsltvdgftdpsnserfclgllsnvnr
natvemtrrhigrgvrlyyiggevfaeclsdsaifvqspncnqrpatvckippgcnlkif
nnqefaallaqsvnqgfeavyqltrmctirmsfvkgwgaeyrrqtvtstpcwielhlngp
lqwldkvltqm

Timeline for d5xoda1:

• d5xoda1 first appeared in SCOPe 2.07