Lineage for d1ddsb_ (1dds B:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)
  7. Species Escherichia coli [TaxId:562] [53600] (86 PDB entries)
  8. Domain d1ddsb_: 1dds B: [34859]
    complexed with ca, cl, mtx

Details for d1ddsb_

PDB Entry: 1dds (more details), 2.2 Å

PDB Description: molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate
PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d1ddsb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ddsb_ c.71.1.1 (B:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

SCOPe Domain Coordinates for d1ddsb_ are not available.

Timeline for d1ddsb_:

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Domains from other chains:
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d1ddsa_