Lineage for d2drca_ (2drc A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2136851Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)
  7. 2136861Species Escherichia coli [TaxId:562] [53600] (78 PDB entries)
  8. 2136912Domain d2drca_: 2drc A: [34848]
    complexed with ca, cl, mtx

Details for d2drca_

PDB Entry: 2drc (more details), 1.9 Å

PDB Description: investigation of the functional role of tryptophan-22 in escherichia coli dihydrofolate reductase by site-directed mutagenesis
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d2drca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2drca_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}

SCOPe Domain Coordinates for d2drca_:

Click to download the PDB-style file with coordinates for d2drca_.
(The format of our PDB-style files is described here.)

Timeline for d2drca_: