SCOPe 2.07: Domain d5x3vb_: 5x3v B:

Lineage for d5x3vb_ (5x3v B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.4: GABA-aminotransferase-like [53417] (17 proteins)
   formerly omega-Aminoacid:pyruvate aminotransferase-like

6. Protein Serine hydroxymethyltransferase [53429] (8 species)

7. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [142671] (9 PDB entries)
   Uniprot P34897 42-504

8. Domain d5x3vb_: 5x3v B: [348315]
   automated match to d3ou5a_
   complexed with so4; mutant

Details for d5x3vb_

PDB Entry: 5x3v, 2.85 Å

PDB Description: structure of human shmt2 protein mutant

PDB Compounds: (B:) Serine hydroxymethyltransferase, mitochondrial

SCOPe Domain Sequences for d5x3vb_:

Sequence, based on SEQRES records:

>d5x3vb_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
wtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnnrysegypg
kryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytallqphdrim
gldlpdgghlthgymsdvkrisatsiffesmpyklnpktglidynqlaltarlfrprlii
agtsayarlidyarmrevcdevkahlladmahisglvaakvipspfkhadivtttthktl
rgarsglifyrkgvkavdpktgreipytfedrinfavfpslqggphnhaiaavavalkqa
ctpmfreyslqvlknaramadallergyslvsggtdnhlvlvdlrpkgldgaraervlel
vsitankntcpgdrsaitpgglrlgapaltsrqfreddfrrvvdfidegvniglevkskt
aklqdfksfllkdsetsqrlanlrqrveqfarafpmpgfdeh

Sequence, based on observed residues (ATOM records):

>d5x3vb_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
wtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnnrysegypg
kryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytallqphdrim
gldlpdgghlrisatsiffesmpyklnpktglidynqlaltarlfrprliiagtsayarl
idyarmrevcdevkahlladmahisglvaakvipspfkhadivtttthktlrgarsglif
yrkgvipytfedrinfavfpslqggphnhaiaavavalkqactpmfreyslqvlknaram
adallergyslvsggtdnhlvlvdlrpkgldgaraervlelvsitankntcpgdsaitpg
glrlgapaltsrqfreddfrrvvdfidegvniglevksktaklqdfksfllkdsetsqrl
anlrqrveqfarafpmpgfdeh

Timeline for d5x3vb_:

• d5x3vb_ is new in SCOPe 2.07-stable
  
• d5x3vb_ appears in the current release, SCOPe 2.08