Lineage for d5w8lc1 (5w8l C:1-159)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2429095Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 2429134Protein Lactate dehydrogenase [51859] (19 species)
  7. 2429200Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (29 PDB entries)
  8. 3048085Domain d5w8lc1: 5w8l C:1-159 [348147]
    Other proteins in same PDB: d5w8la2, d5w8lb2, d5w8lc2, d5w8ld2
    automated match to d4jnka1
    complexed with 9ya, edo, nai

Details for d5w8lc1

PDB Entry: 5w8l (more details), 1.95 Å

PDB Description: crystal structure of lactate dehydrogenase a in complex with inhibitor compound 59 and nadh
PDB Compounds: (C:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d5w8lc1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5w8lc1 c.2.1.5 (C:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvig

SCOPe Domain Coordinates for d5w8lc1:

Click to download the PDB-style file with coordinates for d5w8lc1.
(The format of our PDB-style files is described here.)

Timeline for d5w8lc1:

  • d5w8lc1 appears in periodic updates to SCOPe 2.07 starting on 2018-04-06